Metabolomics (WG-M)

IFCC free webinar: "Metabolomics: Promises and Clinical Translation Challenges"

February 15, 2023

Click here to watch the webinar

Click here to attend the webinar and receive the "Certificate of Participation"
at the end of the webinar after replying to three questions

Comprehensive metabolic profiling, using metabolomics, has become widely accepted as a dynamic and sensitive measure of the phenotype at the molecular level, placing the technology at the forefront of biomarker and mechanistic discoveries related to pathophysiological processes. Small molecule metabolites involved in cellular function, maintenance, differentiation, growth and death are of particular interest for biologists and clinicians as potential biomarkers of pathophysiological processes to facilitate disease diagnosis and prognosis (i.e, prediction of risk and/or disease progression).

This presentation covers the concepts of metabolomics and the recent advances of analytical methods used to generate metabolomics data.

Different applications of metabolomics are presented with particular emphasis on lipidomics applications as well as real world implementation of NMR blood testing in clinical routine.

This webinar comprises of three following presentations of 20 min each followed by 20 min of panel discussion at the end.

Chair: Dr. Fux Elie

Talk 1- "Introduction to metabolomics in the clinical laboratory"  - Dr. Fux Elie

Talk 2- "Lipidomic applications" - Dr. Anne K Bendt

Talk 3- "Real-world implementation of NMR blood testing " - Dr. James D. Otvos

Membership

Terms of Reference 

1. Assess Metabolomics approaches and Identify barriers/ challenges for clinical applications .
2. Recommend solutions to facilitate the translation from academic laboratories to clinical laboratories

Objectives 

1. To evaluate and monitor emerging trends of Research in the field of Metabolomics.
2. To provide an overview on metabolite discovery strategies by combining metabolomics with orthogonal experimental and computational biology approaches.
3. To assess the applications of Metabolomics in clinical diagnosis and prognosis.
4. To develop periodic updates of the applications on Metabolomics technologies and methods in clinical diagnosis.
5. To assess the accessibility and the barriers to routine implementation of Metabolomics in clinical laboratories.
6. To develop a resource that will inform the IFCC community on developments in the applications of Metabolomics in Clinical Diagnosis /Prognosis as well as methods/technologies in the IVD Market.

List of Corresponding Members, nominated by National Societies

Working Group Chair contacts:

Dr. Elie Fux
Group Head Analytics - Early Development
Roche Diagnostics Penzberg - Germany
E-mail: elie.fux@roche.com