Advancing excellence in laboratory medicine for better healthcare worldwide

Standardisation of Hemoglobin A2 (WG-HbA2)

Joint Working Group with ICSH (International Council for Standardization in Haematology)


Name Position Country Term Time in Office
G. Arsene Chair DE 1st 2023 01 - 2025 12
G. Auclair Member BE    
P. Kaiser Member DE    
A. Mosca Member IT    
R. Paleari Member IT    
L. Wu  Member CN    
T. Zhang Member CN    



Terms of Reference

  • To promote the standardization of hemoglobin A2 measurement through the definition of an international reference system, including a reference measurement procedure and primary and secondary reference materials.


Current Projects

  • Definition of a Reference Measurement Procedure (RMP) using mass spectrometry associated with proteolytic degradation. The method will have to be developed in compliance with the ISO 15193 standard and, at the end, listed in the JCTLM database.
  • Preparation of a certified Reference Material (CRM) for hemoglobin A2, in cooperation with the Joint Research Center (BE).
  • Implementation of the standardization on a worldwide scale, by following the roadmap recently developed, in collaboration with the ICSH.
  • Preparation of a complementary matrix material for HbA2, to be used in Quality control programs.


List of Corresponding Members, nominated by National Societies

Name Full and Affiliate Member Societies
Michel Arock Société Française de Biologie Clinique (SFBC)
Fazıla Erkal Turkish Biochemical Society (TBS)
Olufemi Akanni Association of Clinical Chemists Nigeria (ACCN)
Marijana Dajak Society of Medical Biochemists of Serbia (DMBS)


List of Corresponding Members, nominated by Corporate Members

Name Corporate Members
Marco Flamini BIO RAD Laboratories
Frédéric Robert SEBIA S.A




Working Group Chair's contact

Cristian Gabriel ARSENE
Physikalisch-Technische Bundesanstalt (PTB)

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