Contributed by
Manole Cojocaru, IFCC representative Romania, President
Symposium
Over the past several years, medicine has started to
recognize the fundamental role of inflammation in nearly every
disease process. The inflammatory response is an attempt by the
body to restore and maintain homeostasis after injury and is an
integral part of body defences. Inflammation is essentially
beneficial, however, excess or prolonged inflammation can cause
harm. Researchers and physicians have been redefining heart
disease, Alzheimer's and even diabetes and obesity as inflammatory
disorders.
After the
great success of the 1st National Symposium "Inflammation
2004"which was held on April of 2004 in Sambata de Sus, Brasov
County, the Second Symposium "Inflammation 2006" of the Romanian
Society of Laboratory Medicine was held in Poiana Brasov, Brasov
County, between 6-8 April 2006, under the auspices of the Romanian
Academy of Medical Sciences. The title of the symposium was
"Inflammation and Inflammatory Diseases". Distinguished Romanian
and Foreign Scientists informed us about the updated developments
on the research, diagnostic and therapeutic sector of inflammatory
diseases. The Symposium brought together the most prominent names
and sophisticated expert in the fields of medical biochemistry,
molecular biology, genetics, immunology, pharmacology, thrombosis
and hemostasis, molecular medicine and other related branches.
Recent research indicates that the immune system and inflammatory
reactions are governed and regulated by powerful neuronal mediators
derived from the central and peripheral nervous system.
Dr. Manole Cojocaru, senior researcher, President of the
Symposium, welcomed approximatley 130 experts from country and
Europe, Canada and USA as participants in the Symposium. There were
over 50 scientific papers presented (plenary lectures, oral
communications), as well as a workshop on quantitative analysis of
serum free immunoglobulin light chains by automated immunoassay.
Knowledge of the immune system has expanded dramatically in the
last decades, not at least due to enormous developments in
molecular biology and biotechnology. The impact of immunology on
clinical medicine is, however, still not in balance with the
progress in our understanding of the immune system and the
potentials for immunointervention. Nevertheless, clinical
immunology has evolved recently into a discipline that contributes
to medicine not only by giving insight into the pathogenesis of
many diseases but also by offering huge possibilities for diagnosis
and treatment of those diseases. Immunology has emerged as a
clinically relevant discipline in almost every field of medicine.
As the understanding of immunology continues to rapidly evolve, the
clinical immunologist should be the bridge between immunology and
clinical medicine, and translate these developments into daily
clinical practice. An exhibition of the instruments and diagnostic
reagents and drugs took place within the Symposium. The Symposium
dealt with topics primarily related to issues of recent progress in
inflammation research, new technologies and standards in laboratory
medicine, the role of laboratory medicine based on evidence, the
quality of analytic testing and requirements for competent
laboratories for testing. Some of the specific topics covered were:
pathophysiology of inflammation, inflammation/infection,
inflammatory diseases as risk or trigger factors for human ischemic
stroke, markers of oxidative stress and redox modification in
chronic inflammation in end stage renal disease, evaluation of
endothelial dysfunction in humans, inflammatory response of the
brain following cerebral ischemia, cell volume regulation relation
to ischemia and cell proliferation, the effect of NO synthase and
lipoxygenase blockade on oxidative stress and experimental shock.
The participation of national and international diagnostics
companies definitely contributed to the success of this event. The
Second Symposium "Inflammation 2006" was successful and was widely
acclaimed. Special thanks again to all for a truly internationally
friendly meeting in Poiana Brasov, Brasov County.
In conclusion, the investigations during the past five
decades and advances in molecular biology, biochemistry, and
genetics have contributed to the formulation of modern concepts of
immunobiology in inflammation. Following the Second Symposium will
be found a CD which the reader may find useful. The next Symposium
on inflammation is planned to take place in 2008.
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